Publications

Selected Publications

Peters CJ, Gilchrist JM, Tien J, Bethel NP, Qi L, Chen T, Wang L, Jan YN, Grabe M, Jan LY. The Sixth Transmembrane Segment Is a Major Gating Component of the TMEM16A Calcium-Activated Chloride Channel. Neuron. 2018 Mar 7;97(5):1063-1077.e4. doi: 10.1016/j.neuron.2018.01.048. Epub 2018 Feb 22. PubMed PMID: 29478917; PubMed Central PMCID: PMC5860880.

Dang S, Feng S, Tien J, Peters CJ, Bulkley D, Lolicato M, Zhao J, Zuberbühler K, Ye W, Qi L, Chen T, Craik CS, Jan YN, Minor DL Jr, Cheng Y, Jan LY. Cryo-EM structures of the TMEM16A calcium-activated chloride channel. Nature. 2017 Dec 21;552(7685):426-429. doi: 10.1038/nature25024. Epub 2017 Dec 13. PubMed PMID: 29236684; PubMed Central PMCID: PMC5750132.

Peters CJ, Yu H, Tien J, Jan YN, Li M, Jan LY. Four basic residues critical for the ion selectivity and pore blocker sensitivity of TMEM16A calcium-activated chloride channels. Proc Natl Acad Sci U S A. 2015 Mar 17;112(11):3547-52. doi: 10.1073/pnas.1502291112. Epub 2015 Mar 2. PubMed PMID: 25733897; PubMed Central PMCID: PMC4371966.

Tien J*, Peters CJ*, Wong XM, Cheng T, Jan YN, Jan LY, Yang H. A comprehensive search for calcium binding sites critical for TMEM16A calcium-activated chloride channel activity. Elife. 2014 Jun 30;3. doi: 10.7554/eLife.02772. PubMed PMID: 24980701; PubMed Central PMCID: PMC4112547. (* denotes equal contribution)

Peters CJ, Fedida D, Accili EA. Allosteric coupling of the inner activation gate to the outer pore of a potassium channel. Sci Rep. 2013 Oct 23;3:3025. doi: 10.1038/srep03025. PubMed PMID: 24149575; PubMed Central PMCID: PMC3806241.

Peters CJ, Werry D, Gill HS, Accili EA, Fedida D. Mechanism of accelerated current decay caused by an episodic ataxia type-1-associated mutant in a potassium channel pore. J Neurosci. 2011 Nov 30;31(48):17449-59. doi: 10.1523/JNEUROSCI.2940-11.2011. PubMed PMID: 22131406.

Click here for a full list of Dr. Peters' publications at NCBI